![]() ![]() Its affinity, albeit low, for histamine receptors contributes to anticholinergic effects. Alpha-1 adrenergic effects are responsible for orthostatic hypotension. Risperidone blocks dopamine receptors resulting in extrapyramidal symptoms. Risperidone is an atypical antipsychotic that is a selective monoaminergic antagonist with strong affinity for serotonin type 2 (5-HT2) receptors and slightly weaker affinity for dopamine type 2 (D2) receptors. Management is mainly supportive and symptomaticįor 24 hour advice, contact the Poisons Information Centre 13 11 26 Background.Serious effects include cardiac instability such as arrhythmias and neurological instability including CNS depression, seizures and extra pyramidal symptoms.Risperidone is an atypical antipsychotic agent associated with tachycardia and acute dystonic reactions.Poisoning – acute guidelines for initial management Resuscitation Anticholinergic Syndrome Key points ![]()
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